Longitudinal study of adverse reactions following diphtheria-tetanus-pertussis vaccine in infancy
SS Long, A Deforest, DG Smith, C Lazaro… - …, 1990 - publications.aap.org
A prospective study of immunogenicity and adverse effects of 1553 doses of diphtheria and
tetanus toxoids and whole cell pertussis vaccine (DTP) was performed in 538 children
observed longitudinally from 2 months to 20 months of age. Subjects were randomized to
the standard four-dose immunization schedule or to a three-dose schedule (with a saline
injection substituted for DTP at 6 months of age). The three-dose schedule could not be
recommended on the basis of serologic data. Compliance for completing a clinical …
tetanus toxoids and whole cell pertussis vaccine (DTP) was performed in 538 children
observed longitudinally from 2 months to 20 months of age. Subjects were randomized to
the standard four-dose immunization schedule or to a three-dose schedule (with a saline
injection substituted for DTP at 6 months of age). The three-dose schedule could not be
recommended on the basis of serologic data. Compliance for completing a clinical …