Unrecognized glucose intolerance is common in pulmonary arterial hypertension

ME Pugh, IM Robbins, TW Rice, J West… - The Journal of heart and …, 2011 - Elsevier
Background Animal and human data suggest insulin resistance is common in pulmonary
arterial hypertension (PAH). Although routine assessment of insulin resistance is difficult,
hemoglobin A 1c (HbA 1c) is a sensitive test to detect diabetes mellitus (DM) and those at
high risk for DM. We aimed to define the prevalence of elevated HbA 1c in PAH patients and
to correlate HbA 1c levels with functional assessment. Methods HbA 1c was measured in 41
PAH patients without a diagnosis of DM, along with demographic, functional, and …