Maternal high-fat intake predisposes nonalcoholic fatty liver disease in C57BL/6 offspring
BM Gregorio, V Souza-Mello, JJ Carvalho… - American journal of …, 2010 - Elsevier
OBJECTIVE: This work aimed to verify the hypothesis that maternal intake of high-fat diet in
critical periods of pregnancy and/or suckling period predisposes nonalcoholic fatty liver
disease in adult C57BL/6 mice offspring. STUDY DESIGN: Male pups were divided into 5
groups:(1) SC, from standard chow–fed dams;(2) G, from high-fat chow (HF)–fed dams
during the gestation (G) period;(3) L, from HF-fed dams during the lactation (L) period;(4) GL,
from HF-fed dams during the gestation and lactation (GL) periods; and (5) GL/HF, from HF …
critical periods of pregnancy and/or suckling period predisposes nonalcoholic fatty liver
disease in adult C57BL/6 mice offspring. STUDY DESIGN: Male pups were divided into 5
groups:(1) SC, from standard chow–fed dams;(2) G, from high-fat chow (HF)–fed dams
during the gestation (G) period;(3) L, from HF-fed dams during the lactation (L) period;(4) GL,
from HF-fed dams during the gestation and lactation (GL) periods; and (5) GL/HF, from HF …
