Relationship between the omega-3 index and specialized pro-resolving lipid mediators in patients with peripheral arterial disease taking fish oil supplements
MS Schaller, GJ Zahner, WJ Gasper, WS Harris… - Journal of clinical …, 2017 - Elsevier
Background Oral supplementation with n-3 polyunsaturated fatty acids (PUFA) increases the
omega-3 index, a biomarker of red blood cell eicosapentaenoic acid and docosahexaenoic
acid, and plasma levels of biosynthesis pathway markers and potent lipid mediators
involved in the resolution of inflammation among patients with peripheral arterial disease
(PAD). Objective We aimed to quantify the association between an upstream change in the
omega-3 index and downstream changes in lipid mediator production. Methods We …
omega-3 index, a biomarker of red blood cell eicosapentaenoic acid and docosahexaenoic
acid, and plasma levels of biosynthesis pathway markers and potent lipid mediators
involved in the resolution of inflammation among patients with peripheral arterial disease
(PAD). Objective We aimed to quantify the association between an upstream change in the
omega-3 index and downstream changes in lipid mediator production. Methods We …