Epidemiological and economic effects of priming with the whole-cell Bordetella pertussis vaccine

H DeAngelis, SV Scarpino, MC Fitzpatrick… - JAMA …, 2016 - jamanetwork.com
Importance Current acellular pertussis vaccines may not protect against transmission
ofBordetella pertussis. Objective To assess whether a priming dose of whole-cell pertussis
(wP) vaccine is cost-effective at reducing pertussis infection in infants. Design, Setting, and
Participants Mathematical model of pertussis transmission fit to US incidence data in a
simulation of the US population. In this simulation study conducted from June 2014 to May
2015, the population was divided into 9 age groups corresponding to the current pertussis …