Using acellular pertussis vaccines for childhood immunization. Potential benefits far outweigh potential risks.
DA Conrad, HB Jenson - Postgraduate medicine, 1999 - europepmc.org
DA Conrad, HB Jenson
Postgraduate medicine, 1999•europepmc.orgIf acellular vaccines can offer protection against pertussis that is similar to that afforded by
whole-cell vaccines and do so with reduced adverse effects, why have these agents not
completely replaced the whole-cell preparations? This article provides an overview of
general characteristics of both types of vaccine and some concerns and issues that remain
in many physicians' minds. In addition, the authors furnish a rationale and recommendations
for safe and appropriate use of the newer acellular formulations.
whole-cell vaccines and do so with reduced adverse effects, why have these agents not
completely replaced the whole-cell preparations? This article provides an overview of
general characteristics of both types of vaccine and some concerns and issues that remain
in many physicians' minds. In addition, the authors furnish a rationale and recommendations
for safe and appropriate use of the newer acellular formulations.
If acellular vaccines can offer protection against pertussis that is similar to that afforded by whole-cell vaccines and do so with reduced adverse effects, why have these agents not completely replaced the whole-cell preparations? This article provides an overview of general characteristics of both types of vaccine and some concerns and issues that remain in many physicians' minds. In addition, the authors furnish a rationale and recommendations for safe and appropriate use of the newer acellular formulations.
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