Empiric antibiotic treatment reduces mortality in severe sepsis and septic shock from the first hour: results from a guideline-based performance improvement program
R Ferrer, I Martin-Loeches, G Phillips… - Critical care …, 2014 - journals.lww.com
Objectives: Compelling evidence has shown that aggressive resuscitation bundles,
adequate source control, appropriate antibiotic therapy, and organ support are cornerstone
for the success in the treatment of patients with sepsis. Delay in the initiation of appropriate
antibiotic therapy has been recognized as a risk factor for mortality. To perform a
retrospective analysis on the Surviving Sepsis Campaign database to evaluate the
relationship between timing of antibiotic administration and mortality. Design: Retrospective …
adequate source control, appropriate antibiotic therapy, and organ support are cornerstone
for the success in the treatment of patients with sepsis. Delay in the initiation of appropriate
antibiotic therapy has been recognized as a risk factor for mortality. To perform a
retrospective analysis on the Surviving Sepsis Campaign database to evaluate the
relationship between timing of antibiotic administration and mortality. Design: Retrospective …