[HTML][HTML] Evidence for overlapping and distinct functions in protein transport of coat protein Sec24p family members
R Peng, A De Antoni, D Gallwitz - Journal of Biological Chemistry, 2000 - ASBMB
Budding of transport vesicles from the endoplasmic reticulum in yeast requires the formation,
at the budding site, of a coat protein complex (COPII) that consists of two heterodimeric
subcomplexes (Sec23p/Sec24p and Sec13p/Sec31p) and the Sar1 GTPase. Sec24p is an
essential protein and involved in cargo selection. In addition to Sec24p, the yeast
Saccharomyces cerevisiae expresses two non-essential Sec24p-related proteins, termed
Sfb2p (product of YNL049c) and Sfb3p/Lst1p (product of YHR098c). We here show that …
at the budding site, of a coat protein complex (COPII) that consists of two heterodimeric
subcomplexes (Sec23p/Sec24p and Sec13p/Sec31p) and the Sar1 GTPase. Sec24p is an
essential protein and involved in cargo selection. In addition to Sec24p, the yeast
Saccharomyces cerevisiae expresses two non-essential Sec24p-related proteins, termed
Sfb2p (product of YNL049c) and Sfb3p/Lst1p (product of YHR098c). We here show that …