Neutrophil–lymphocyte ratio reflects hepatocellular carcinoma recurrence after liver transplantation via inflammatory microenvironment

T Motomura, K Shirabe, Y Mano, J Muto, T Toshima… - Journal of …, 2013 - Elsevier
BACKGROUND & AIMS: Although the Milan criteria (MC) have been used to select liver
transplantation candidates among patients with hepatocellular carcinoma (HCC), many
patients exceeding the MC have shown good prognosis. Preoperative neutrophil–
lymphocyte ratio (NLR) is a predictor of patient prognosis, but its mechanism has never been
clarified. METHODS: We assessed outcomes in 158 patients who had undergone living-
donor liver transplantation (LDLT) for HCC. Recurrence-free survival (RFS) was determined …