[3] Liver cell lines

GJ Darlington - 1987 - Elsevier
Publisher Summary This chapter describes two lines that well characterized with respect to
their expression of differentiated function and are derived from the same transplantable
tumor type—the BW7756 tumor carried in C57 leaden/J mice. While the culture and
maintenance of normal diploid hepatocytes as a proliferating population have been difficult
tasks, the growth of transformed hepatocyte-derived cell lines appears to be relatively
uncomplicated. Techniques that are suitable for fibroblast culture are also suitable for …