[PDF][PDF] EMT and MET in metastasis: where are the cancer stem cells?

T Brabletz - Cancer cell, 2012 - cell.com
Cancer cell, 2012cell.com
Activation of epithelial-mesenchymal transition (EMT) is important for cancer cell
dissemination. Two papers in this issue of Cancer Cell (Ocaņa and colleagues and Tsai and
colleagues) support the concept that the reversal of EMT is necessary for efficient metastatic
colonization. Moreover, although EMT has been associated with stemness properties, one
study indicates that they are not necessarily linked.
Activation of epithelial-mesenchymal transition (EMT) is important for cancer cell dissemination. Two papers in this issue of Cancer Cell (Ocaņa and colleagues and Tsai and colleagues) support the concept that the reversal of EMT is necessary for efficient metastatic colonization. Moreover, although EMT has been associated with stemness properties, one study indicates that they are not necessarily linked.
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