[HTML][HTML] Expression of hypoxia-inducible factors in the peri-implantation mouse uterus is regulated in a cell-specific and ovarian steroid hormone-dependent manner …
T Daikoku, H Matsumoto, RA Gupta, SK Das… - Journal of Biological …, 2003 - ASBMB
Increased uterine vascular permeability and angiogenesis are hallmarks of implantation and
placentation. These events are profoundly influenced by vascular endothelial growth factor
(VEGF). We previously showed that VEGF isoforms and VEGF receptors are expressed in
the uterus, suggesting the role of VEGF in uterine vascular permeability and angiogenesis
required for implantation and decidualization. We have recently shown that estrogen
promotes uterine vascular permeability but inhibits angiogenesis, whereas progesterone …
placentation. These events are profoundly influenced by vascular endothelial growth factor
(VEGF). We previously showed that VEGF isoforms and VEGF receptors are expressed in
the uterus, suggesting the role of VEGF in uterine vascular permeability and angiogenesis
required for implantation and decidualization. We have recently shown that estrogen
promotes uterine vascular permeability but inhibits angiogenesis, whereas progesterone …