Resolvins, protectins and maresins are individual families of specialized pro-resolving
mediators biosynthesized from the dietary n-3 polyunsaturated fatty acids eicosapentaenoic
acid and docosahexaenoic acid. These enzymatically oxygenated polyunsaturated lipid
mediators were first elucidated during the resolution phase of acute inflammation in animal
models of self-limited inflammation. Specialized pro-resolving mediators display potent
bioactions when administrated in vivo. Biosynthetic pathway studies have revealed that …