Rainbow trout (Oncorhynchus mykiss) brain cells biosynthesize novel docosahexaenoic acid-derived resolvins and protectins—mediator lipidomic analysis
S Hong, E Tjonahen, EL Morgan, Y Lu… - Prostaglandins & other …, 2005 - Elsevier
Docosahexaenoic acid (DHA; C22: 6 n− 3) is an abundant fatty acid in fish phospholipids. In
the present study, we employed liquid chromatography–ultraviolet spectrometry–tandem
mass spectrometry and dissociated rainbow trout (Oncorhynchus mykiss) brain cells to
determine whether fish utilize endogenous DHA to produce the recently uncovered novel
lipid mediators termed the resolvins and protectins, generated by mammalian cells [Serhan
CN, Hong S, Gronert K, et al. Resolvins: a family of bioactive products of omega-3 fatty acid …
the present study, we employed liquid chromatography–ultraviolet spectrometry–tandem
mass spectrometry and dissociated rainbow trout (Oncorhynchus mykiss) brain cells to
determine whether fish utilize endogenous DHA to produce the recently uncovered novel
lipid mediators termed the resolvins and protectins, generated by mammalian cells [Serhan
CN, Hong S, Gronert K, et al. Resolvins: a family of bioactive products of omega-3 fatty acid …