[HTML][HTML] CD44 isoforms in normal and leukemic hematopoiesis
S Ghaffari, F Smadja-Joffe, R Oostendorp… - Experimental …, 1999 - Elsevier
The CD44 family of adhesion molecules is a fascinating group of highly glycosylated
proteins encoded by a single gene. The various isoforms produced are differentially
expressed in many cell types, where they are involved in a wide range of biological
processes [1]. Initially, CD44 cell surface molecules were identified and named according to
their reactivity with particular monoclonal antibodies (mAb). This resulted in the rapid
accumulation of a highly confusing terminology [eg, Pgp-1, Ln (Lu)-related p80, ECM III …
proteins encoded by a single gene. The various isoforms produced are differentially
expressed in many cell types, where they are involved in a wide range of biological
processes [1]. Initially, CD44 cell surface molecules were identified and named according to
their reactivity with particular monoclonal antibodies (mAb). This resulted in the rapid
accumulation of a highly confusing terminology [eg, Pgp-1, Ln (Lu)-related p80, ECM III …