[HTML][HTML] Biophysics of sphingolipids I. Membrane properties of sphingosine, ceramides and other simple sphingolipids

FM Goņi, A Alonso - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2006 - Elsevier
Biochimica et Biophysica Acta (BBA)-Biomembranes, 2006Elsevier
Some of the simplest sphingolipids, namely sphingosine, ceramide, some closely related
molecules (eicosasphingosine, phytosphingosine), and their phosphorylated compounds
(sphingosine-1-phosphate, ceramide-1-phosphate), are potent metabolic regulators. Each of
these lipids modifies in marked and specific ways the physical properties of the cell
membranes, in what can be the basis for some of their physiological actions. This paper
reviews the mechanisms by which these sphingolipid signals, sphingosine and ceramide in …
Some of the simplest sphingolipids, namely sphingosine, ceramide, some closely related molecules (eicosasphingosine, phytosphingosine), and their phosphorylated compounds (sphingosine-1-phosphate, ceramide-1-phosphate), are potent metabolic regulators. Each of these lipids modifies in marked and specific ways the physical properties of the cell membranes, in what can be the basis for some of their physiological actions. This paper reviews the mechanisms by which these sphingolipid signals, sphingosine and ceramide in particular, are able to modify the properties of cell membranes.
Elsevier