Plasmablastic lymphoma in HIV-positive patients: an aggressive Epstein-Barr virus-associated extramedullary plasmacytic neoplasm

HY Dong, DT Scadden, L de Leval, Z Tang… - The American journal …, 2005 - journals.lww.com
AIDS-associated aggressive B-cell lymphomas often have plasmacytoid features. Plasma
cell neoplasms in HIV patients were commonly described to have atypical morphology and
an aggressive clinical course in the literature. We reviewed 14 cases of neoplasms with
marked plasmacytic differentiation in HIV-positive patients to determine their
clinicopathologic features. Of these, 13 of 14 had homogeneous morphology and were
generally CD45+, CD20−, PAX-5−, and CD138+. All were positive for Epstein-Barr virus …