Cortically induced thalamic plasticity in the primate somatosensory system
ER Ergenzinger, MM Glasier, JO Hahm… - Nature neuroscience, 1998 - nature.com
ER Ergenzinger, MM Glasier, JO Hahm, TP Pons
Nature neuroscience, 1998•nature.comThe influence of cortical feedback on receptive field organization in the thalamus was
assessed in the primate somatosensory system. Chronic and acute suppression of neuronal
activity in primary somatosensory cortex resulted in a striking enlargement of receptive fields
in the ventroposterior thalamus. This finding demonstrates a dramatic'top-down'influence of
cortex on receptive field size in the somatosensory thalamus. In addition, this result has
important implications for studies of adult neuronal plasticity because it indicates that …
assessed in the primate somatosensory system. Chronic and acute suppression of neuronal
activity in primary somatosensory cortex resulted in a striking enlargement of receptive fields
in the ventroposterior thalamus. This finding demonstrates a dramatic'top-down'influence of
cortex on receptive field size in the somatosensory thalamus. In addition, this result has
important implications for studies of adult neuronal plasticity because it indicates that …
Abstract
The influence of cortical feedback on receptive field organization in the thalamus was assessed in the primate somatosensory system. Chronic and acute suppression of neuronal activity in primary somatosensory cortex resulted in a striking enlargement of receptive fields in the ventroposterior thalamus. This finding demonstrates a dramatic'top-down'influence of cortex on receptive field size in the somatosensory thalamus. In addition, this result has important implications for studies of adult neuronal plasticity because it indicates that changes in'higher-order'areas of the brain can trigger extensive changes in the receptive field characteristics of neurons located earlier in the processing pathway.
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