Experience with immunomodulatory treatments in Rasmussen's encephalitis
T Granata, L Fusco, G Gobbi, E Freri, F Ragona… - Neurology, 2003 - AAN Enterprises
T Granata, L Fusco, G Gobbi, E Freri, F Ragona, G Broggi, R Mantegazza, L Giordano…
Neurology, 2003•AAN EnterprisesThe authors investigated immunomodulatory treatments in 15 patients with Rasmussen
encephalitis (RE)(14 with childhood and one with adolescent onset RE). Positive time-
limited responses were obtained in 11 patients using variable combinations of
corticosteroids, apheresis, and high-dose IV immunoglobulins. Although surgical exclusion
of the affected hemisphere is the only treatment that halts disease progression,
immunomodulation can be considered when early surgery is not feasible, in late-onset …
encephalitis (RE)(14 with childhood and one with adolescent onset RE). Positive time-
limited responses were obtained in 11 patients using variable combinations of
corticosteroids, apheresis, and high-dose IV immunoglobulins. Although surgical exclusion
of the affected hemisphere is the only treatment that halts disease progression,
immunomodulation can be considered when early surgery is not feasible, in late-onset …
The authors investigated immunomodulatory treatments in 15 patients with Rasmussen encephalitis (RE) (14 with childhood and one with adolescent onset RE). Positive time-limited responses were obtained in 11 patients using variable combinations of corticosteroids, apheresis, and high-dose IV immunoglobulins. Although surgical exclusion of the affected hemisphere is the only treatment that halts disease progression, immunomodulation can be considered when early surgery is not feasible, in late-onset patients with slower disease progression, and in the few cases of bilateral disease.
American Academy of Neurology