[HTML][HTML] Vaccines against tuberculosis: where are we and where do we need to go?
THM Ottenhoff, SHE Kaufmann - PLoS pathogens, 2012 - journals.plos.org
PLoS pathogens, 2012•journals.plos.org
In this review we discuss recent progress in the development, testing, and clinical evaluation
of new vaccines against tuberculosis (TB). Over the last 20 years, tremendous progress has
been made in TB vaccine research and development: from a pipeline virtually empty of new
TB candidate vaccines in the early 1990s, to an era in which a dozen novel TB vaccine
candidates have been and are being evaluated in human clinical trials. In addition,
innovative approaches are being pursued to further improve existing vaccines, as well as …
of new vaccines against tuberculosis (TB). Over the last 20 years, tremendous progress has
been made in TB vaccine research and development: from a pipeline virtually empty of new
TB candidate vaccines in the early 1990s, to an era in which a dozen novel TB vaccine
candidates have been and are being evaluated in human clinical trials. In addition,
innovative approaches are being pursued to further improve existing vaccines, as well as …
In this review we discuss recent progress in the development, testing, and clinical evaluation of new vaccines against tuberculosis (TB). Over the last 20 years, tremendous progress has been made in TB vaccine research and development: from a pipeline virtually empty of new TB candidate vaccines in the early 1990s, to an era in which a dozen novel TB vaccine candidates have been and are being evaluated in human clinical trials. In addition, innovative approaches are being pursued to further improve existing vaccines, as well as discover new ones. Thus, there is good reason for optimism in the field of TB vaccines that it will be possible to develop better vaccines than BCG, which is still the only vaccine available against TB.
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