Toxic epidermal necrolysis and Stevens-Johnson syndrome: a review
R Gerull, M Nelle, T Schaible - Critical care medicine, 2011 - journals.lww.com
Objectives: The aims of this review are to summarize the definitions, causes, and clinical
course as well as the current understanding of the genetic background, mechanism of
disease, and therapy of toxic epidermal necrolysis and Stevens-Johnson syndrome. Data
Sources: PubMed was searched using the terms toxic epidermal necrolysis, Stevens-
Johnson syndrome, drug toxicity, drug interaction, and skin diseases. Data Synthesis: Toxic
epidermal necrolysis and Stevens-Johnson syndrome are acute inflammatory skin reactions …
course as well as the current understanding of the genetic background, mechanism of
disease, and therapy of toxic epidermal necrolysis and Stevens-Johnson syndrome. Data
Sources: PubMed was searched using the terms toxic epidermal necrolysis, Stevens-
Johnson syndrome, drug toxicity, drug interaction, and skin diseases. Data Synthesis: Toxic
epidermal necrolysis and Stevens-Johnson syndrome are acute inflammatory skin reactions …