Corticosteroids and wound healing: clinical considerations in the perioperative period
AS Wang, EJ Armstrong, AW Armstrong - The American journal of surgery, 2013 - Elsevier
Background Determining whether systemic corticosteroids impair wound healing is a
clinically relevant topic that has important management implications. Methods We reviewed
literature on the effects of corticosteroids on wound healing from animal and human studies
searching MEDLINE from 1949 to 2011. Results Some animal studies show a 30%
reduction in wound tensile strength with perioperative corticosteroids at 15 to 40 mg/kg/day.
The preponderance of human literature found that high-dose corticosteroid administration …
clinically relevant topic that has important management implications. Methods We reviewed
literature on the effects of corticosteroids on wound healing from animal and human studies
searching MEDLINE from 1949 to 2011. Results Some animal studies show a 30%
reduction in wound tensile strength with perioperative corticosteroids at 15 to 40 mg/kg/day.
The preponderance of human literature found that high-dose corticosteroid administration …