Etanercept therapy for toxic epidermal necrolysis
Background Toxic epidermal necrolysis (TEN) is a severe and potentially lethal drug
reaction for which no standard treatment is available. Objective To describe a case series of
patients with TEN treated with a single dose of etanercept. Methods We observed 10
consecutive patients with TEN. For each patient, we recorded the presence of comorbidities
and all the drugs recently started (ie, in the last month). In all cases, 50 mg of etanercept was
administered in a single subcutaneous injection. The clinical severity of disease was …
reaction for which no standard treatment is available. Objective To describe a case series of
patients with TEN treated with a single dose of etanercept. Methods We observed 10
consecutive patients with TEN. For each patient, we recorded the presence of comorbidities
and all the drugs recently started (ie, in the last month). In all cases, 50 mg of etanercept was
administered in a single subcutaneous injection. The clinical severity of disease was …