Brown adipose tissues (BAT) are derived from a myogenic factor 5 (Myf5)-expressing cell
lineage and white adipose tissues (WAT) predominantly arise from non-Myf5 lineages,
although a subpopulation of adipocytes in some WAT depots can be derived from the Myf5
lineage. However, the functional implication of the Myf5-and non-Myf5-lineage cells in WAT
is unclear. We found that the Myf5-lineage constitution in subcutaneous WAT depots is
negatively correlated to the expression of classical BAT and newly defined beige/brite …