Thy-1-interacting molecules and cellular signaling in cis and trans

R Herrera-Molina, A Valdivia, M Kong, A Alvarez… - International review of …, 2013 - Elsevier
Abstract Thy-1, discovered almost 50 years ago, was for many years a subject of great
scientific interest. The putative functions attributed to this molecule could not be confirmed
due, at least in part, to a ligand that took a long time to be identified. This chapter describes
the properties of Thy-1 and the regulation of its expression. Also, the interactions that have
been described for Thy-1 in both cis and trans, and the signaling mechanisms reported to
emanate from such interactions are discussed. The consequences of Thy-1-activated …