[HTML][HTML] Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family

WM Yang, YL Yao, JM Sun, JR Davie, E Seto - Journal of Biological …, 1997 - ASBMB
Several human cDNAs encoding a histone deacetylase protein, HDAC3, have been
isolated. Analysis of the predicted amino acid sequence of HDAC3 revealed an open
reading frame of 428 amino acids with a predicted molecular mass of 49 kDa. The HDAC3
protein is 50% identical in DNA sequence and 53% identical in protein sequence compared
with the previously cloned human HDAC1. Comparison of the HDAC3 sequence with
human HDAC2 also yielded similar results, with 51% identity in DNA sequence and 52 …