Human milk oligosaccharides: prebiotics and beyond
L Bode - Nutrition reviews, 2009 - academic.oup.com
Nutrition reviews, 2009•academic.oup.com
Human milk oligosaccharides (HMO) are complex glycans that are present at very high
concentrations in human milk but not in infant formula. The significant energy expended by
mothers to make these complex glycans suggests they must be important. How do maternal
HMOs benefit the breast-fed infant? How are HMOs synthesized in the human mammary
gland? How can we provide formula-fed infants with HMOs or HMO-like glycans? This article
reviews current knowledge and open questions on the biosynthesis and functions of HMOs.
concentrations in human milk but not in infant formula. The significant energy expended by
mothers to make these complex glycans suggests they must be important. How do maternal
HMOs benefit the breast-fed infant? How are HMOs synthesized in the human mammary
gland? How can we provide formula-fed infants with HMOs or HMO-like glycans? This article
reviews current knowledge and open questions on the biosynthesis and functions of HMOs.
Abstract
Human milk oligosaccharides (HMO) are complex glycans that are present at very high concentrations in human milk but not in infant formula. The significant energy expended by mothers to make these complex glycans suggests they must be important. How do maternal HMOs benefit the breast-fed infant? How are HMOs synthesized in the human mammary gland? How can we provide formula-fed infants with HMOs or HMO-like glycans? This article reviews current knowledge and open questions on the biosynthesis and functions of HMOs.
Oxford University Press