Rare emergence of symptoms during long-term asymptomatic Escherichia coli 83972 carriage without an altered virulence factor repertoire

B Köves, E Salvador, J Grönberg-Hernández… - The Journal of …, 2014 - Elsevier
Purpose Asymptomatic bacteriuria established by intravesical inoculation of Escherichia coli
83972 is protective in patients with recurrent urinary tract infections. In this randomized,
controlled crossover study a total of 3 symptomatic urinary tract infection episodes
developed in 2 patients while they carried E. coli 83972. We examined whether virulence
reacquisition by symptom isolates may account for the switch from asymptomatic bacteriuria
to symptomatic urinary tract infection. Materials and Methods We used E. coli 83972 re …