Protective effect of quercetin on ER stress caused by calcium dynamics dysregulation in intestinal epithelial cells
Y Natsume, S Ito, H Satsu, M Shimizu - Toxicology, 2009 - Elsevier
Quercetin, one of the flavonoids present in plants, expresses several physiological functions
including antioxidative and anti-inflammatory properties. However, its effect on intestinal
epithelia remains to be elucidated. Endoplasmic reticulum (ER) stress has been attracting
considerable attention since ER stress triggers such disorders as inflammation and cancer.
The effect of quercetin on ER stress was investigated in this present study. Several ER stress
inducers (tunicamycin, A23187, thapsigargin and brefeldin A) were added to human colonic …
including antioxidative and anti-inflammatory properties. However, its effect on intestinal
epithelia remains to be elucidated. Endoplasmic reticulum (ER) stress has been attracting
considerable attention since ER stress triggers such disorders as inflammation and cancer.
The effect of quercetin on ER stress was investigated in this present study. Several ER stress
inducers (tunicamycin, A23187, thapsigargin and brefeldin A) were added to human colonic …