[PDF][PDF] SnapShot: astrocytes in health and disease

S Liddelow, B Barres - Cell, 2015 - cell.com
S Liddelow, B Barres
Cell, 2015cell.com
Astrocytes are central nervous system (CNS) glial cells with many important functions for
normal development and neural functioning. They help control extracellular ion and
neurotransmitter concentrations; provide neurotrophic support; are implicated in synapse
formation, function, and pruning; and help maintain the blood-brain barrier. Following injury
and in disease, they undergo rapid and chronic alterations in function that can either
promote or hinder recovery, depending on the disease.
Astrocytes are central nervous system (CNS) glial cells with many important functions for normal development and neural functioning. They help control extracellular ion and neurotransmitter concentrations; provide neurotrophic support; are implicated in synapse formation, function, and pruning; and help maintain the blood-brain barrier. Following injury and in disease, they undergo rapid and chronic alterations in function that can either promote or hinder recovery, depending on the disease.
cell.com