Enhanced survival and differentiation in vitro of different neuronal populations by some interleukins
SC Moroni, A Rossi - International journal of developmental neuroscience, 1995 - Elsevier
Data from the literature demonstrate the existence of a growing family of neuropoietic
cytokines; members of this group have structural motifs in common with other members and
with neurotrophic factors. In this research we studied the responses elicited in vitro by some
of these molecules in two different neuronal populations: murine neuroblastoma N18TG2
and neurons from chicken dorsal root ganglia. Both IL-2 and IL-6 improve the survival of
murine neuroblastoma cells in clonal density plating experiments; in addition IL-2 …
cytokines; members of this group have structural motifs in common with other members and
with neurotrophic factors. In this research we studied the responses elicited in vitro by some
of these molecules in two different neuronal populations: murine neuroblastoma N18TG2
and neurons from chicken dorsal root ganglia. Both IL-2 and IL-6 improve the survival of
murine neuroblastoma cells in clonal density plating experiments; in addition IL-2 …