Incidence of hepatic metastases for various neoplasms in several strains of mice

CH Frith - Toxicologic Pathology, 1983 - journals.sagepub.com
CH Frith
Toxicologic Pathology, 1983journals.sagepub.com
The incidence of hepatic metastases for a variety of spontaneous and carcinogen-induced
malignant neoplasms was studied in several strains of mice. Forty percent of osteogenic
sarcomas metastasized to the liver in C57BL/6 female mice. Fourteen percent of
mesotheliomas metastasized to the liver in C3H mice and 11.5% of alveolar/bronchiolar
carcinomas metastasized to the liver in BALB/c male mice. All other malignant neoplasms
metastasized to the liver at a rate of less than 10% and most at less than 5%.
The incidence of hepatic metastases for a variety of spontaneous and carcinogen-induced malignant neoplasms was studied in several strains of mice. Forty percent of osteogenic sarcomas metastasized to the liver in C57BL/6 female mice. Fourteen percent of mesotheliomas metastasized to the liver in C3H mice and 11.5% of alveolar/bronchiolar carcinomas metastasized to the liver in BALB/c male mice. All other malignant neoplasms metastasized to the liver at a rate of less than 10% and most at less than 5%.
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