Comparison of myelin, axon, lipid, and immunopathology in the central nervous system of differentially myelin-compromised mutant mice: a morphological and …
G Loers, F Aboul-Enein, U Bartsch, H Lassmann… - Molecular and Cellular …, 2004 - Elsevier
The present study was carried out to compare different myelin-compromised mouse mutants
with regard to myelin morphology in relation to axon-, lipid-, and immunopathology as a
function of age. Mouse mutants deficient in the myelin-associated glycoprotein (MAG) and
myelin basic protein (MBP) display subtle and severe myelin pathologies in the central
nervous system (CNS), respectively. Animals doubly deficient in MAG and the neural cell
adhesion molecule (NCAM) show defects similar to those present in MAG single mutants …
with regard to myelin morphology in relation to axon-, lipid-, and immunopathology as a
function of age. Mouse mutants deficient in the myelin-associated glycoprotein (MAG) and
myelin basic protein (MBP) display subtle and severe myelin pathologies in the central
nervous system (CNS), respectively. Animals doubly deficient in MAG and the neural cell
adhesion molecule (NCAM) show defects similar to those present in MAG single mutants …