Inclusion of full length human immunodeficiency virus type 1 (HIV-1) gag sequences in viral recombinants applied to drug susceptibility phenotyping
LH Robinson, CV Gale, JP Kleim - Journal of virological methods, 2002 - Elsevier
Drug susceptibility phenotyping of recombinant clinical human immunodeficiency virus type
1 (HIV-1) isolates has been used widely to quantitatively assess viral resistance to
antiretroviral agents. A novel method is described for HIV-1 drug susceptibility phenotyping.
Recombinant virus that contains the entire HIV-1 Gag, protease (PR) and reverse
transcriptase (RT) coding regions is generated from plasma of HIV-1 infected subjects, thus
allowing the in vitro investigation of effects caused by all protein-coding sequence elements …
1 (HIV-1) isolates has been used widely to quantitatively assess viral resistance to
antiretroviral agents. A novel method is described for HIV-1 drug susceptibility phenotyping.
Recombinant virus that contains the entire HIV-1 Gag, protease (PR) and reverse
transcriptase (RT) coding regions is generated from plasma of HIV-1 infected subjects, thus
allowing the in vitro investigation of effects caused by all protein-coding sequence elements …