Modified disease activity scores that include twenty‐eight‐joint counts development and validation in a prospective longitudinal study of patients with rheumatoid …

MLL Prevoo, MA Van'T Hof, HH Kuper… - … : Official Journal of …, 1995 - Wiley Online Library
MLL Prevoo, MA Van'T Hof, HH Kuper, MA Van Leeuwen, LBA Van De Putte, P Van Riel
Arthritis & Rheumatism: Official Journal of the American College …, 1995Wiley Online Library
Objective. The development and validation of Modified Disease Activity Scores (DAS) that
include different 28‐joint counts. Methods. These scores were developed by canonical
discriminant analyses and validated for criterion, correlational, and construct validity. The
influence of disease duration on the composition of the DAS was also investigated. Results.
No influence of disease duration was found. The Modified DAS that included 28‐joint counts
were able to discriminate between high and low disease activity (as indicated by clinical …
Abstract
Objective. The development and validation of Modified Disease Activity Scores (DAS) that include different 28‐joint counts.
Methods. These scores were developed by canonical discriminant analyses and validated for criterion, correlational, and construct validity. The influence of disease duration on the composition of the DAS was also investigated.
Results. No influence of disease duration was found. The Modified DAS that included 28‐joint counts were able to discriminate between high and low disease activity (as indicated by clinical decisions of rheumatologists).
Conclusion. The Modified DAS are as valid as disease activity scores that include more comprehensive joint counts.
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