The existence of immunologic infertility is well grounded in the theories of humoral and cell-
mediated immunology. Both of these immune system arms can theoretically and
experimentally be shown to play roles in states of male factor infertility. Although much
progress has been made in relating immunopathology to infertility, several problems plague
the investigation and diagnosis: the use of multiple, different assay systems; the lack of
properly controlled experimental work; a need to oversimplify a tremendously complex …