Non transferrin bound iron (NTBI) in acute leukemias throughout conventional intensive chemotherapy: kinetics of its appearance and potential predictive role in …

A Belotti, L Duca, L Borin, S Realini, R Renso… - Leukemia Research, 2015 - Elsevier
We analyzed appearance of non transferrin bound iron (NTBI) in 30 transplant eligible
patients with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) during
conventional chemotherapy treatment program and evaluated possible relationship with
transfusional body iron intake, iron parameters and clinical complications. For each course,
serum samples for NTBI detection were taken prior to chemotherapy, during treatment and
during subsequent bone marrow myelosuppression: NTBI was assessed by HPLC …