[HTML][HTML] Olaparib monotherapy in patients with advanced cancer and a germline BRCA1/2 mutation

B Kaufman, R Shapira-Frommer… - Journal of clinical …, 2015 - ncbi.nlm.nih.gov
B Kaufman, R Shapira-Frommer, RK Schmutzler, MW Audeh, M Friedlander, J Balmaña…
Journal of clinical oncology, 2015ncbi.nlm.nih.gov
Olaparib Monotherapy in Patients With Advanced Cancer and a Germline BRCA1/2
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Abstract
Purpose
Olaparib is an oral poly (ADP-ribose) polymerase inhibitor with activity in germline BRCA1 and BRCA2 (BRCA1/2)–associated breast and ovarian cancers. We evaluated the efficacy and safety of olaparib in a spectrum of BRCA1/2-associated cancers.
ncbi.nlm.nih.gov