[PDF][PDF] “Ring-fencing” BRCA1 tumor suppressor activity
Cancer Cell, 2011•cell.com
``Ring-Fencing'' BRCA1 Tumor Suppressor Activity Page 1 the immunostimulatory versus
immunosuppressive effects of IL-10 remains alive and well. ACKNOWLEDGMENTS The
authors wish to acknowledge funding support from the National Health and Medical Research
Council of Australia, the Prostate Cancer Foundation of Australia, the Victorian Cancer
Agency, and the Cancer Council of Victoria. REFERENCES Fujii, S., Shimizu, K., Shimizu, T.,
and Lotze, MT (2001). Blood 98, 2143–2151. Girardi, M., Glusac, E., Filler, RB, Roberts, SJ …
immunosuppressive effects of IL-10 remains alive and well. ACKNOWLEDGMENTS The
authors wish to acknowledge funding support from the National Health and Medical Research
Council of Australia, the Prostate Cancer Foundation of Australia, the Victorian Cancer
Agency, and the Cancer Council of Victoria. REFERENCES Fujii, S., Shimizu, K., Shimizu, T.,
and Lotze, MT (2001). Blood 98, 2143–2151. Girardi, M., Glusac, E., Filler, RB, Roberts, SJ …
BRCA1 is a crucial human breast and ovarian cancer tumor suppressor gene. The article by Drost et al. in this issue of Cancer Cell together with a recent paper in Science now provide a clearer picture of how this large and complex protein suppresses tumorigenesis.
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