Netrins
BJ Dickson, K Keleman - Current Biology, 2002 - cell.com
BJ Dickson, K Keleman
Current Biology, 2002•cell.comWhat are they? Netrins are a conserved family of secreted proteins that guide migrating cells
and axonal growth cones. The name is derived from the Sanskrit 'netr', meaning 'one who
guides'. They are 70–80 kDa in size, with some homology to laminin, including a series of
three EGF-like repeats. There is one netrin in worms, two in flies, and at least two each in
chicks, mice and men.
and axonal growth cones. The name is derived from the Sanskrit 'netr', meaning 'one who
guides'. They are 70–80 kDa in size, with some homology to laminin, including a series of
three EGF-like repeats. There is one netrin in worms, two in flies, and at least two each in
chicks, mice and men.
What are they? Netrins are a conserved family of secreted proteins that guide migrating cells and axonal growth cones. The name is derived from the Sanskrit ‘netr’, meaning ‘one who guides’. They are 70–80 kDa in size, with some homology to laminin, including a series of three EGF-like repeats. There is one netrin in worms, two in flies, and at least two each in chicks, mice and men.
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