Evidence supporting a role for blockade of the vascular endothelial growth factor system in the pathophysiology of preeclampsia: Young Investigator Award
OBJECTIVE: Soluble vascular endothelial growth factor receptor 1 (sVEGFR-1), which
antagonizes VEGF functions, has been implicated in the pathophysiology of preeclampsia.
The purpose of this study was to determine whether preeclampsia is associated with a
change in the plasma concentration of sVEGFR-1, and, if so, whether such a change is
correlated with the severity of the disease. METHODS: A cross-sectional study was
conducted to determine the concentrations of sVEGFR-1 in plasma obtained from normal …
antagonizes VEGF functions, has been implicated in the pathophysiology of preeclampsia.
The purpose of this study was to determine whether preeclampsia is associated with a
change in the plasma concentration of sVEGFR-1, and, if so, whether such a change is
correlated with the severity of the disease. METHODS: A cross-sectional study was
conducted to determine the concentrations of sVEGFR-1 in plasma obtained from normal …