[HTML][HTML] Expression of B-cell surface antigens in subpopulations of exosomes released from B-cell lymphoma cells

MP Oksvold, A Kullmann, L Forfang, B Kierulf, M Li… - Clinical …, 2014 - Elsevier
Purpose Exosomes are small (30-to 100-nm) vesicles secreted by all cell types in culture
and found in most body fluids. A mean of 1 mL of blood serum, derived from healthy donors,
contains approximately 10 12 exosomes. Depending on the disease, the number of
exosomes can fluctuate. Concentration of exosomes in the bloodstream and all other body
fluids is extremely high. Several B-cell surface antigens (CD19, CD20, CD22, CD23, CD24,
CD37, CD40, and HLA-DR) and the common leukocyte antigen CD45 are interesting in …