Support for a proposed retinoid-processing protein complex in apical retinal pigment epithelium

VL Bonilha, SK Bhattacharya, KA West, JS Crabb… - Experimental eye …, 2004 - Elsevier
The interaction of cellular retinaldehyde-binding protein (CRALBP) with ERM (ezrin, radixin,
moesin)-binding phosphoprotein 50 (EBP50) in retinal pigment epithelium (RPE)
microsomes has led to the hypothesis that a retinoid-processing protein complex exists in
apical RPE. Mouse RPE apical processes were isolated on wheat germ agglutinin-coated
agarose beads. Proteomic analyses of the isolated apical RPE demonstrated the presence
of CRALBP, EBP50, 11-cis-retinol dehydrogenase, cellular retinol-binding protein 1, and …