Classic Kaposi sarcoma in 3 unrelated Turkish children born to consanguineous kindreds
G Sahin, A Palanduz, G Aydogan, O Cassar… - …, 2010 - publications.aap.org
Infection by human herpesvirus 8 (HHV-8) in childhood is common in the Mediterranean
basin; however, classic Kaposi sarcoma (KS) is exceedingly rare in children not infected
with HIV and not receiving immunosuppression, with only 30 cases having been reported
since 1960. We recently reported 2 children with autosomal and X-linked recessive primary
immunodeficiencies underlying KS in a context of multiple clinical manifestations. These
reports suggested that classic KS in otherwise healthy children might also result from inborn …
basin; however, classic Kaposi sarcoma (KS) is exceedingly rare in children not infected
with HIV and not receiving immunosuppression, with only 30 cases having been reported
since 1960. We recently reported 2 children with autosomal and X-linked recessive primary
immunodeficiencies underlying KS in a context of multiple clinical manifestations. These
reports suggested that classic KS in otherwise healthy children might also result from inborn …