Context The role of diet composition in response to overeating and energy dissipation in
humans is unclear. Objective To evaluate the effects of overconsumption of low, normal, and
high protein diets on weight gain, energy expenditure, and body composition. Design,
Setting, and Participants A single-blind, randomized controlled trial of 25 US healthy, weight-
stable male and female volunteers, aged 18 to 35 years with a body mass index between 19
and 30. The first participant was admitted to the inpatient metabolic unit in June 2005 and …