The use of urinary albumin-creatinine ratios and calcium-creatinine ratios as screening tests for pregnancy-induced hypertension
PN Baker, GA Hackett - Obstetrics & Gynecology, 1994 - journals.lww.com
PN Baker, GA Hackett
Obstetrics & Gynecology, 1994•journals.lww.comObjective: To assess the potential of both urinary albumincreatinine ratios and urinary
calcium-creatinine ratios as screening tests for pregnancy-induced hypertension. Methods:
A prospective, non-interventional study was performed in a teaching hospital antenatal
clinic. Five hundred normotensive, nulliparous pregnant women provided a urine sample at
19 weeks' gestation. The main outcome measurements were the development of pregnancy-
induced hypertension and preeclampsia. Results: No significant differences in urinary …
calcium-creatinine ratios as screening tests for pregnancy-induced hypertension. Methods:
A prospective, non-interventional study was performed in a teaching hospital antenatal
clinic. Five hundred normotensive, nulliparous pregnant women provided a urine sample at
19 weeks' gestation. The main outcome measurements were the development of pregnancy-
induced hypertension and preeclampsia. Results: No significant differences in urinary …
Abstract
Objective:
To assess the potential of both urinary albumincreatinine ratios and urinary calcium-creatinine ratios as screening tests for pregnancy-induced hypertension.
Methods:
A prospective, non-interventional study was performed in a teaching hospital antenatal clinic. Five hundred normotensive, nulliparous pregnant women provided a urine sample at 19 weeks' gestation. The main outcome measurements were the development of pregnancy-induced hypertension and preeclampsia.
Results:
No significant differences in urinary albumin/creatinine and calcium/creatinine were demonstrated between patients who developed pregnancy-induced hypertension and those who remained normotensive. Urinary creatinine concentrations were significantly higher at 19 weeks' gestation in patients who subsequently developed pregnancy-induced hypertension.
Conclusions:
This study suggests that neither urinary ratio is a potential screening test for pregnancy-induced hypertension. The increased urinary creatinine concentration in patients who subsequently developed pregnancyinduced hypertension has not previously been reported and merits further investigation.(Obstet Gynecol 1994; 83: 745-9)
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