[PDF][PDF] Acute abnormalities of sensory nerve function associated with oxaliplatin-induced neurotoxicity
Journal of clinical Oncology, 2009•researchgate.net
Purpose Neurotoxicity is becoming increasingly recognized as the major dose-limiting
toxicity of oxaliplatin. Because the mechanism of oxaliplatin-induced neurotoxicity remains
unclear, the present study investigated the potential of axonal excitability techniques in
identifying pathophysiologic mechanisms and early markers of nerve dysfunction.
toxicity of oxaliplatin. Because the mechanism of oxaliplatin-induced neurotoxicity remains
unclear, the present study investigated the potential of axonal excitability techniques in
identifying pathophysiologic mechanisms and early markers of nerve dysfunction.
Purpose
Neurotoxicity is becoming increasingly recognized as the major dose-limiting toxicity of oxaliplatin. Because the mechanism of oxaliplatin-induced neurotoxicity remains unclear, the present study investigated the potential of axonal excitability techniques in identifying pathophysiologic mechanisms and early markers of nerve dysfunction.
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