[HTML][HTML] Reanalysis of ATP11B, a type IV P-type ATPase
MS Halleck, RA Schlegel, PL Williamson - Journal of Biological Chemistry, 2002 - ASBMB
P-type ATPases are a venerable family of ATP-dependent ion transporters. Recently,
evidence was presented that a rabbit gene in the type IV subfamily of P-type ATPases was
missing a transmembrane helix (transmembrane domain 4) thought to be critical for ion
transport, a deletion that would place the two major catalytic loops of the enzyme on
opposite sides of the membrane. It was proposed that the resulting protein was a RING
finger-binding protein that targets transcription factors to specific domains within the nucleus …
evidence was presented that a rabbit gene in the type IV subfamily of P-type ATPases was
missing a transmembrane helix (transmembrane domain 4) thought to be critical for ion
transport, a deletion that would place the two major catalytic loops of the enzyme on
opposite sides of the membrane. It was proposed that the resulting protein was a RING
finger-binding protein that targets transcription factors to specific domains within the nucleus …