Acrodermatitis enteropathica and an overview of zinc metabolism
E Maverakis, MA Fung, PJ Lynch, M Draznin… - Journal of the American …, 2007 - Elsevier
Acrodermatitis enteropathica is a rare autosomal recessive disorder of zinc deficiency. The
genetic defect has been mapped to 8q24 and the defective gene identified as SLC39A4,
which encodes the zinc transporter Zip4. The diagnosis is made by way of clinical
presentation together with histopathology and laboratory tests. Here we provide an overview
of zinc metabolism and a description of inherited and acquired zinc deficiency.
genetic defect has been mapped to 8q24 and the defective gene identified as SLC39A4,
which encodes the zinc transporter Zip4. The diagnosis is made by way of clinical
presentation together with histopathology and laboratory tests. Here we provide an overview
of zinc metabolism and a description of inherited and acquired zinc deficiency.