[HTML][HTML] Function of RIG-I-like receptors in antiviral innate immunity
M Yoneyama, T Fujita - Journal of Biological Chemistry, 2007 - ASBMB
Various cells in the body are capable of sensing infectious viruses and initiating reactions
collectively known as antiviral innate responses. These responses include the production of
antiviral cytokines such as type I interferon (IFN) 2 and subsequent synthesis of antiviral
enzymes, which are responsible for the impairment of viral replication and promoting
adaptive immune responses (1). In this minireview, we focus on a subset of molecules
known as RIG-I-like receptors, which sense viral RNA molecules that trigger a danger signal.
collectively known as antiviral innate responses. These responses include the production of
antiviral cytokines such as type I interferon (IFN) 2 and subsequent synthesis of antiviral
enzymes, which are responsible for the impairment of viral replication and promoting
adaptive immune responses (1). In this minireview, we focus on a subset of molecules
known as RIG-I-like receptors, which sense viral RNA molecules that trigger a danger signal.
